منابع مشابه
Human prions and plasma lipoproteins.
Prions are composed solely of an alternatively folded isoform of the prion protein (PrP), designated PrP(Sc). The polyoxometalate phosphotungstic acid has been used to separate PrP(Sc) from its precursor PrP(C) by selective precipitation; notably, native PrP(Sc) has not been solubilized by using nondenaturing detergents. Because of the similarities between PrP(Sc) and lipoproteins with respect ...
متن کاملInteraction of plasma lipoproteins with human platelets.
Human plasma low density lipoproteins (LDL) and high density lipoproteins (HDL) were radioiodinated and their interaction with washed human platelets was assessed. Both ligands were bound by the platelet at 37 degrees C, and an apparent equilibrium was attained within two hours. Minimal binding was observed at 22 degrees C or 4 degrees C. The specificity of these interactions was indicated by t...
متن کاملGradient gel electrophoresis of human plasma lipoproteins.
A rapid and simple method for separating and identifying plasma lipoproteins is described. The technique utilizes the “molecular sieving” properties of continuous concave gradient electrophoresis on a slab of polyacrylamide (4 to 26%) gel. Gradient gel electrophoresis is particularly suitable for separating lipoproteins according to their molecular weight. The technique can be used to demonstra...
متن کاملImmunochemical Studies on Human Plasma Lipoproteins
Low density human plasma lipoproteins S(f) 17+, S(f) 13, and S(f) 6, high density lipoproteins 2 and 3, and a lipoprotein-free plasma protein fraction were isolated from human plasma by ultracentrifugal methods. It was found that human plasma lipoproteins are immunochemically distinct from the non-lipoprotein containing plasma protein fraction. Lipoprotein fractions of a given hydrated density,...
متن کاملEvaluation of plasma lipids and lipoproteins in patients with psoriasis
Psoriasis is an epidermal disease characterized by chronic relapsing papillon squamous erythematous plaques which may develop in the skin of elbows, knees and extensor surfaces. The cause of psoriasis is unknown. The primary etiologic factor may be related to excessive uncontrolled synthesis is resulting from changes in (1) the function of growth factors ( EGF),(2) presence of proto- oncogenes,...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2006
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0604021103